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Celebrating Excellence in Lung Transplant Research & Care

The world’s first successful double-lung transplant for cystic fibrosis (CF) was performed at Toronto General Hospital in 1988. Since then, Canada’s world-renowned surgeons have pioneered new techniques now adopted internationally. Today, they continue to pursue ground-breaking research, innovating to achieve paradigm-shifting, world-first milestones. Funding from Cystic Fibrosis Canada (CF Canada) helps to support improvements in transplantation processes and outcomes through its research and healthcare programs.

Canadian National Transplant Research Program

From 2013 – 2017, CF Canada partnered with the Canadian Institutes for Health Research (CIHR) to support the Canadian National Transplant Research Program (CNTRP), an initiative aimed at addressing challenges in organ donation and transplantation. The CNTRP brings together basic and clinical researchers, health economists, and experts in policy, law, and ethics. The collaborative program includes more than 30 sites across the country and members are tackling 7 major projects to increase access to transplantation and improve survival and quality of life post-transplant. Given the success of the first 5 years of the program, CF Canada has renewed its support through 2021. In total, CF Canada will contribute $160,000 to the initiative. Read our Spotlight on Research to learn more about the CNTRP.

Transplant Centre Incentive Grants

CF Canada provides Transplant Centre Incentive Grants annually to support transplant centres across Canada. According to the Canadian CF Registry, 694 individuals with CF received a lung transplant in Canada between 1988 and 2016.1 Canada has one of the highest post-transplant survival rates in the world for people with CF. The probability of surviving one year after lung transplant is almost 90 % and 10 years is 50 %.2

Developing National Standards to Successfully Transition Transplant Patients with CF

With generous support from Vertex’s Circle of Care program, CF Canada has joined forces with Dr. Cecilia Chaparro, transplant physician at the University Health Network-Toronto General Hospital, and Kate Gent, previously Nurse Coordinator at the Adult CF Clinic at St. Michael’s Hospital (now at SickKids), Toronto. Together, the group is developing national standards to successfully transition transplant patients with CF. The aims of this initiative are to understand the current challenges and gaps in care for transplant patients, provide educational resources for patients and caregivers, and host training workshops for healthcare professionals. Further details on the program can be found here.

 

To learn more about the exciting progress in lung transplantation made by Canadian researchers and physicians, please view the summary below.

 

  1. Cystic Fibrosis Canada. The Canadian Cystic Fibrosis Registry: 2016 Annual Data Report. Toronto; 2017.
  2. Stephenson A.L., et al. Clinical and demographic factors associated with post-lung transplantation survival in individuals with cystic fibrosis. J Heart Lung Transplant. 2015;34(9):1139-1145.